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  1. Gebrauchsanweisung
  2. Heckman JD, Ryaby JP, McCabe J, Frey JJ, Kilcoyne RF. (1994) Acceleration of Tibial Fracture-Healing by Non-Invasive, Low-Intensity Pulsed Ultrasound. J Bone Joint Surg 76 (1): 26-34
  3. Nolte PA, van der Krans A, Patka P, Janssen IMC, Ryaby JP, Albers GHR. (2001) Low-intensity pulsed ultrasound in the treatment of nonunions. J Trauma 51(4): 693-703
  4. Azuma Y., Ito M., Harada Y., Takagi H., Ohta T., Jingushi S. (2001) Low intensity pulsed ultrasound accelerates rat femoral fracture healing by acting on the various cellular reactions in the fracture callus, J. Bone Miner. Res. 16 (4) : 671–680
  5. Rubin, C., Bolander, M., Ryaby, J. P. & Hadjiargyrou, M. (2001) The Use of Low-Intensity Ultrasound to Accelerate the Healing of Fractures J. Bone Jt. Surg. 83-A: 259–270
  6. Siska PA, Gruen GS, Pape HC.(2008) External adjuncts to enhance fracture healing: What is the role of ultrasound? Injury. 39:1095-1105.
  7. Kristiansen et al. (1997) J Bone Joint Surg Am. 79:961-73
  8. K.S. Leung, W.S. Lee, H.F. Tsui, P.P.L. Liu, W.H. Cheung. (2004) Complex tibial fracture outcomes following treatment with low-intensity pulsed ultrasound, Ultrasound Med. Biol. 30 (3) :389–395
  9. Coughlin MJ, Smith BW, Traughber P. (2008) The evaluation of the healing rate of subtalar arthrodeses, part 2: the effect of low-intensity ultrasound stimulation. Foot Ankle Int. 29(10):970-7.
  10. Pounder NM, Harrison AJ. (2008) Low intensity pulsed ultrasound for fracture healing: a review of the clinical evidence and the associated biological mechanism of action. Ultrasonics. 48(4):330-8. Epub 2008 Mar 27.
  11. Zhou et al. (2008) Cell Signal. 20(4):695-704
  12. Cook SD, Ryaby JP, McCabe J, Frey JJ, Heckman JD, Kristiansen TK (1997) Acceleration of Tibia and Distal Radius Fracture Healing in Patients Who Smoke. Clin. Orthop. Rel. Res. 337: 198–207
  13. Freeman TA et al. (2009) J Orthop Res. 27(5):673-9
  14. Sant'Anna EF et al. (2005) Journal of Orthopaedic Research. 23: 646–652
  15. Ebisawa K, Hata K, Okada K, Kimata K, Ueda M, Torii S, Watanabe H (2004) Ultrasound enhances transforming growth factor beta-mediated chondrocyte differentiation of human mesenchymal stem cells. Tiss. Eng. 10 (5-6): 921-929
  16. Mukai S et al. (2005) Ultrasound in Med. & Biol. 31 (12): 1713–1721
  17. Leung KS, Cheung WH, Zhang C, Lee KM, Lo HK. (2004) Low intensity pulsed ultrasound stimulates osteogenic activity of human periosteal cells. Clin Orthop Rel Res 418: 253-259
  18. Naruse K et al. (2010) Ultrasound in Med. & Biol. 36 (7): 1098–1108
  19. Tang CH et al. (2006) Mol Pharmacol 69:2047–2057
  20. Hayton MJ et al. (2005) Ultrasound in Med. & Biol. 31 (8): 1131–1138
  21. Sena K, Leven RM, Mazhar K, Sumner DR, Virdi AS (2005) Early gene response to low-intensity pulsed ultrasound in rat osteoblastic cells. Ultrasound in Med. & Biol. 31: 703-708
  22. Wang F-S, Kuo Y-R, Wang C-J, Yang KD, Chang P-R, Huang Y-T, Huang H-C, Sun Y-C, Yang Y-J, Chen Y-J (2004) Nitric oxide mediates ultrasound-induced hypoxia-inducible factor-1α activation and vascular endothelial growth factor-A expression in human osteoblasts. Bone 35: 114-123
  23. Internal S&N Company data
  24. FDA PMA P900009/Supplement 6, Summary and Effectiveness Data

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